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ChemSynt 301 Chemical Synthesis Reactor

Compact, fully integrated, modular, and scalable laboratory reaction workstation enabling precise control of temperature, pH, reagent dosing, and magnetic or mechanical stirring. Remote control and data logging ensure safe, reproducible, unattended experimentation.
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ChemSynt 301 Chemical Synthesis ReactorSA110A0710
ChemSynt 301 Chemical Reaction Station no CPF110A0710
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Parallelize. Optimize. Scale Up.

Parallelize. Optimize. Scale Up.

ChemSynt 301 is a compact, modular reaction station designed to perform and control chemical synthesis with precision, safety, and real-time data acquisition. 

It features a modular architecture designed for maximum flexibility and scalability. A single leader unit can control up to three additional reaction stations, enabling up to four independent experiments to run in parallel under different conditions.

Each unit operates independently while remaining fully integrated within the system, supporting efficient reaction screening, process development, and optimization.
This scalable approach allows laboratories to increase throughput as requirements evolve, without compromising control, reproducibility, or data quality.

Every synthesis workflow is different. Configure your ChemSynt 301 in just a few steps and get started: click here!
 
Adaptive Temperature Control with Integrated Heating and Cooling

Adaptive Temperature Control with Integrated Heating and Cooling

Temperature is one of the most critical parameters in chemical synthesis, influencing reaction performance, selectivity, and reproducibility. ChemSynt 301 combines integrated Peltier cooling and electrical heating to provide precise temperature control from -30 °C to +150 °C, extendable to -40 °C with an external chiller.

Programmable temperature profiles and continuous monitoring of both Reaction Temperature (Tr) and Jacket Temperature (Tj) ensure accurate reaction management and reliable data collection throughout the experiment.
  • Temperature range from -30 °C to +150 °C (-40 °C with external chiller)
  • Integrated heating and cooling in a single platform
  • Programmable temperature profiles and ramps
  • Real-time monitoring of Tr and Tj with continuous data logging
Combined Mixing for Scalable Chemistry

Combined Mixing for Scalable Chemistry

Efficient stirring is essential for heat and mass transfer and for reaction reproducibility. ChemSynt 301 supports both magnetic and mechanical stirring, allowing users to select the most suitable mixing strategy for different process requirements.

Three PTFE impeller geometries help replicate industrial mixing conditions, while the compact overhead stirrer ensures easy installation and reliable operation.
  • Magnetic and mechanical stirring in a single platform
  • Three PTFE impeller configurations for process development and scale-up
  • Improved mixing, heat transfer, and solid suspension
  • Compact overhead stirrer with quick screw-lock coupling
Dosing Designed for Reproducible Synthesis

Dosing Designed for Reproducible Synthesis

Accurate reagent addition is essential for reaction control  and high selectivity. ChemSynt 301 can be equipped with a single or double DU50 Dosing Unit, providing precise and flexible reagent dosing throughout the synthesis process.

Continuous dosing with automatic syringe refilling enables uninterrupted operation during long experiments, while reducing manual intervention and improving process consistency. The result is more reliable data and greater confidence in process optimization and scale-up activities.
  • Single or double DU50 configuration for maximum flexibility
  • Continuous dosing with automatic syringe refilling
  • Reduced operator intervention and improved process consistency
  • Reliable support for process optimization and scale-up studies
Dynamic pH Monitoring and Control

Dynamic pH Monitoring and Control

pH is a critical parameter in chemical synthesis, affecting reaction pathways, selectivity, and final product quality. ChemSynt 301 continuously monitors pH and allows users to define target setpoints for different reaction stages.

When paired with the optional DU50 Dosing Unit, the system automatically adds acids or bases to maintain the desired pH, ensuring consistent and reproducible reaction conditions.
  • Continuous pH monitoring with real-time data logging
  • User-defined pH setpoints for automated control
  • Automatic acid/base dosing with the optional DU50
  • Improved process understanding and reproducibility
Every Second Counts. Every Insight Matters.

Every Second Counts. Every Insight Matters.

ChemSynt 301 features intuitive control through both touchpad and PC software, enabling simple setup and efficient operation.

The integrated data logger continuously records key parameters such as temperature and pH at a frequency of one data point per second, generating a complete dataset for every experiment.

Data can be monitored locally or remotely, providing real-time visibility of reaction progress and supporting informed process optimization and decision-making.
 

Models

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Velp.com

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Velp.com
25mL syringe
cod. A00000565
Velp.com
50mL syringe
cod. A00000570
Velp.com
AISI 316 Ti pt100 probe Ø3 ChemSynt 301
cod. A00000587
Velp.com
Clamp for accessories ChemSynt 301
cod. A00000555
Velp.com
Condenser coil 200mm; SJ: 14/23
cod. A00000557
Velp.com
ControllerSoft
cod. A00000391
Velp.com
D3mm 14/20 probe adapter
cod. A00000576
Velp.com
D8mm 14/20 probe adapter
cod. A00000574
Velp.com
Dropping Funnels 100mL; SJ: 14/23
cod. A00000556
Velp.com
DU 50 Dosing Unit
cod. A00000559
Velp.com
DU 50 Double - Dosing Unit
cod. A00000560
Velp.com
Flowmeter pair kit
cod. A00000561
Velp.com
Glass pt100 probe Ø5 ChemSynt 301
cod. A00000572
Velp.com
Glassware kit 100mL for ChemSynt 301
cod. A00000552
Velp.com
Glassware kit 400mL for ChemSynt 301
cod. A00000551
Velp.com
Handle for Block removal
cod. A00000351
Velp.com
Hydraulic insulation kit
cod. A00000564
Velp.com
Hydraulic/pneumatic slave expansion kit
cod. A00000563
Velp.com
Magnetic cross shape stir bar, Ø10x5 mm
cod. A00000336
Velp.com
Magnetic cross shape stir bar, Ø20x8 mm
cod. A00000352
Velp.com
Magnetic disc stir bar, Ø20x10 mm
cod. A00000355
Velp.com
Magnetic stir bar Ø6x20mm
cod. A00001057
Velp.com
Magnetic stir bar, Ø4,5x12 mm
cod. A00001063
Velp.com
Ø16 Vial Adapter for ChemSynt 301
cod. A00000566
Velp.com
OHS RS Digital
cod. A00000558
Velp.com
pH electrode; BNC connector - 320mm
cod. A00000562
Velp.com
PTFE pt100 probe Ø8 ChemSynt 301
cod. A00000553
Velp.com
PTFE Shaft Stirrer, Centrifugal 8x300mm
cod. A00000567
Velp.com
PTFE Shaft Stirrer, Screw Propel 8x300mm
cod. A00000569
Velp.com
PTFE Stir Bar Retriever 350mm
cod. A00000586
Velp.com
PTFE Stirrer Shaft, Retreat Curv 8x300mm
cod. A00000568
Velp.com
PTFE stopper 10/18
cod. A00000578
Velp.com
PTFE stopper 14/20
cod. A00000577
Velp.com
PTFE stopper 19/22
cod. A00000579
Velp.com
Set of 20 glass test tubes Ø 16 mm
cod. CM0091680
Velp.com
Slave connection cable SER158 and ChemSynt
cod. A00000287
Velp.com
Support Kit ChemSynt 301
cod. A00000549

TECHNICAL DATA

Temperature Range -40°C (with chiller) / -30°C to +150°C
Resolution 0.1 K
Temperature Control Mode Jacket temperature control, reaction temperature control
Cooling Peltier cells
Heating Electrical resistance heating
Stirring Magnetic stirring or mechanical stirring (with OHS)
Stirring Speed 50 rpm to 1000 rpm
Data Transfer USB: USB flash drive and/or optional software upgrade
Ethernet - LAN
Software ERMES Cloud Connectivity
ControllerSoft PC Software
Power Supply 115 V / 60 Hz and 230 V / 50-60 Hz
Dimensions (W × D × H) Master Unit: 287 mm × 486 mm × 600 mm
Slave Unit: 232 mm × 326 mm × 281 mm
Weight Master Unit: 12.33 kg
Slave Unit: 10.32 kg

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ChemSynt 301 Chemical Synthesis Reactor

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